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Nutrition & Vitamins

The Signs of Magnesium Deficiency

Dr Ibrar Ahmed MBChB MRCP MRCGP PhD 8 July 2026 5 min read

Magnesium is one of the busiest minerals in the body, involved in hundreds of chemical reactions. It helps your muscles contract and relax, keeps nerves firing correctly, supports a steady heartbeat and plays a part in bone health and energy production. Despite this, it rarely gets much attention until something feels off.

What magnesium does

Most of the body's magnesium is stored in bone and inside cells, with only a small amount circulating in the blood. It acts as a cofactor for enzymes that turn food into energy, regulate the nervous system and keep the electrical activity of the heart in rhythm. It also works in balance with other minerals such as calcium and potassium, which is one reason a shortfall can have knock-on effects.

Signs you might be running low

Mild magnesium deficiency can be subtle and easy to overlook. When symptoms do appear, they often reflect the mineral's role in muscle and nerve function:

These symptoms are non-specific, meaning they can have many causes. That is exactly why guessing is unreliable and a blood test is helpful when magnesium is a genuine suspect.

Key takeaway: magnesium deficiency often shows up as cramps, fatigue and palpitations, but these signs are non-specific — a blood test is the way to confirm whether magnesium is actually low.

Common causes of deficiency

A number of factors can deplete magnesium over time. A diet low in whole grains, nuts, seeds and leafy greens is a common contributor. Other causes include digestive conditions that reduce absorption, persistent diarrhoea or vomiting, certain medications such as some diuretics and long-term stomach-acid reducers, poorly controlled diabetes, and regular high alcohol intake. Older adults are also more prone to low levels.

Recommended test

Check your magnesium

A magnesium test checks for deficiency.

Book a magnesium test

How magnesium is tested

A blood test measures the magnesium circulating in your serum. It is worth knowing that because most magnesium is stored inside cells and bone, blood levels can stay within range even when body stores are modestly depleted. Even so, a blood test remains a practical and widely used way to check, particularly when symptoms or risk factors point towards a shortfall. Your clinician will interpret the result alongside your symptoms and any related minerals.

When to consider a test

Testing can be worthwhile if you have unexplained cramps, palpitations or persistent fatigue, if you take medications known to lower magnesium, or if you have a condition that affects absorption. As with any single result, magnesium is best understood in context rather than in isolation, and any deficiency should be investigated for its cause.

Get checked

Check your magnesium

Book online with OneMedicine — CQC-registered clinic in Birmingham, or a home visit / local clinic nationwide. Doctor-reviewed results, most within 24 hours.

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Dr Ibrar Ahmed
Written by Dr Ibrar Ahmed — MBChB MRCP MRCGP PhD PG Dip (Cardiology)
Specialist interest: Cardiovascular Medicine · OneMedicine, CQC-registered clinic
Medical disclaimer. This article is for general information only and is not a substitute for personal medical advice, diagnosis or treatment. Always speak to a qualified clinician about your individual symptoms and results.